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Ambroxol Hydrochloride

Indications

Ambroxol Hydrochloride is indicated in-

  • Productive cough
  • Acute and chronic inflammatory disorders of upper and lower respiratory tracts associated with viscid mucus including acute and chronic bronchitis
  • Inflammatory disease of rhinopharyngeal tract (laryngitis, pharyngitis, sinusitis and rhinitis) associated with viscid mucus
  • Asthmatic bronchitis bronchial asthma with thick expectoration
  • Bronchiectasis
  • Chronic pneumonia etc.

* রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Pharmacology

Ambroxol is the active metabolite of bromhexine and it has been proven that this metabolite possesses a greater bronchosecretolytic effect than bromhexine. It improves sputum rheology by hydrating mechanism leading to liquefaction of mucus in the lumen of respiratory tract, thus facilitating expectoration of mucus and reducing dyspnea. It stimulates production of phospholipids of surfactant by alveolar cells, thus contributing to the lowering of superficial tension in the alveoli. It also reduces bronchial hyperactivity. Ambroxol has anti inflammatory properties owing to the inhibitory effect on the production of cellular cytokines and arachidonic acid metabolites. In patients with COPD it traditionally improves airway patency.

Dosage & Administration

Average daily dose (preferably after meal):

Pediatric Drops:

  • 0-6 months: 0.5 ml 2 times a day
  • 6-12 months: 1 ml 2 times a day
  • 1-2 years: 1.25 ml 2 times a day

Syrup:

  • 2-5 years: 2.5 ml (1/2 teaspoonful) 2-3 times a day
  • 5-10 years: 5 ml (1 teaspoonful) 2-3 times a day
  • 10 years and adults: 10 ml (2 teaspoonful) 3 times a day.

Sustained release capsule: Adult and children over 12 years old: 1 capsule once daily.

Interaction

Ambroxol should not be taken simultaneously with antitussives (e.g.Codeine) because phlegm, which has been liquefied by Ambroxol might not be expectorated.

Contraindications

Contraindicated in known hypersensitivity to Ambroxol or Bromhexine.

Side Effects

Gastrointestinal side effects like epigastric pain, stomach overfill feeling may occur occasionally. Rarely allergic responses such as eruption, urticaria or angioneurotic edema have been reported.

Pregnancy & Lactation

Teratogenic and fetal toxicity studies have shown no harmful effect of Ambroxol. However, it is advised not to use it in pregnancy, especially during the1st trimester. Safety during lactation has not been established yet.

Precautions & Warnings

Ambroxol should be given cautiously to patients with gastric and duodenal ulceration or convulsive disorders. Patients with hepatic and renal insufficiency should take it with caution.

Therapeutic Class

Cough expectorants & mucolytics

Storage Conditions

Protect from direct light exposure, Store in a dry place at a temperature not exceeding 30°C, Keep out of the reach of children.

Available Brand Names

🌿
Acorex

Apex Pharmaceuticals Ltd.

Unit Price : ৳ 46:00
🌿
Adebrox

Supreme Pharmaceutical Ltd.

Unit Price : ৳ 40.00
🌿
Ambeet

Ethical Drugs Limited

Unit Price : ৳ 40.00
🌿
Ambeet

Ethical Drugs Limited

Unit Price : ৳ 5.00
🌿
Ambix

Modern Pharmaceuticals Ltd.

Unit Price : ৳ 40.00
🌿
Ambocus

OSL Pharma Limited

Unit Price : ৳ 50.00
🌿
Ambocus

OSL Pharma Limited

Unit Price : ৳ 35.00
🌿
Ambokof

Novelta Bestway Pharma Ltd.

Unit Price : ৳ 40.00
🌿
Ambokof

Novelta Bestway Pharma Ltd.

Unit Price : ৳ 30.00
🌿
Ambolin

Virgo Pharmaceuticals Ltd.

Unit Price : ৳ 25.00
🌿
Ambolin

Virgo Pharmaceuticals Ltd.

Unit Price : ৳ 40.00
🌿
Ambolos

S.N. Pharmaceutical Ltd.

Unit Price : ৳ 30.00
🌿
Ambolyt

Incepta Pharmaceuticals Ltd.

Unit Price : ৳ 50.00
🌿
Ambolyt

Incepta Pharmaceuticals Ltd.

Unit Price : ৳ 75.00
🌿
Ambolyt

Incepta Pharmaceuticals Ltd.

Unit Price : ৳ 30.00
🌿
Amboral

Pharmadesh Laboratories Ltd.

Unit Price : ৳ 30.11
🌿
Amboral

Pharmadesh Laboratories Ltd.

Unit Price : ৳ 20.06
🌿
Ambosil

Silva Pharmaceuticals Ltd.

Unit Price : ৳ 40.00
🌿
Ambosil

Silva Pharmaceuticals Ltd.

Unit Price : ৳ 20.00
🌿
Amboten

Eskayef Pharmaceuticals Ltd.

Unit Price : ৳ 50.00
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Amboten

Eskayef Pharmaceuticals Ltd.

Unit Price : ৳ 35.00
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Amboxol

Kumudini Pharma Ltd.

Unit Price : ৳ 42.00
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Amboxol

Kumudini Pharma Ltd.

Unit Price : ৳ 23.00
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Ambozin

Rephco Pharmaceuticals Ltd.

Unit Price : ৳ 40.00
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Ambozin SR

Rephco Pharmaceuticals Ltd.

Unit Price : ৳ 5.00
🌿
Ambrocod

Amulet Pharmaceuticals Ltd.

Unit Price : ৳ 40.00
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Ambrodex

Decent Pharma Laboratories Ltd.

Unit Price : ৳ 40.00
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Ambrodex

Biogen Pharmaceuticals Ltd.

Unit Price : ৳ 40.00
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Ambrokof

Euro Pharma Ltd.

Unit Price : ৳ 45.00
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Ambrokof

Goodman Pharmaceuticals Ltd.

Unit Price : ৳ 40.00
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Ambronaaf

Naafco Pharma Ltd.

Unit Price : ৳ 50.00
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Ambronil

Orion Pharma Ltd.

Unit Price : ৳ 50.00
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Ambronil

Orion Pharma Ltd.

Unit Price : ৳ 30.00
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Ambrop

Bengal drugs Ltd.

Unit Price : ৳ 40.00
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Ambroxol SR

Biopharma Limited

Unit Price : ৳ 5.02
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Ambryl

Jenphar Bangladesh Ltd.

Unit Price : ৳ 45.00
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Ambryl

Jenphar Bangladesh Ltd.

Unit Price : ৳ 34.00
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Amorox

United Pharmaceuticals Ltd.

Unit Price : ৳ 45.00
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Amsiv

Delta Pharma Ltd.

Unit Price : ৳ 45.00
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Aroxol

Healthcare Pharmaceuticals Ltd.

Unit Price : ৳ 50.00
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Aroxol

Healthcare Pharmaceuticals Ltd.

Unit Price : ৳ 35.00
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Axsol

Nipa Pharmaceuticals Ltd.

Unit Price : ৳ 40.00
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Bilco

Doctor’s Chemical Works Ltd.

Unit Price : ৳ 30.00
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Bilco

Doctor’s Chemical Works Ltd.

Unit Price : ৳ 20.00
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Boxol

Opsonin Pharma Ltd.

Unit Price : ৳ 50.00
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Boxol

Opsonin Pharma Ltd.

Unit Price : ৳ 33.00
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Boxol SR

Opsonin Pharma Ltd.

Unit Price : ৳ 5.01
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Broculyt

NIPRO JMI Pharma Ltd.

Unit Price : ৳ 50.00
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Bronchosil

Apollo Pharmaceutical Ltd.

Unit Price : ৳ 38.00
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Bronsol

Pharmik Laboratories Ltd.

Unit Price : ৳ 42.00
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Brox

Navana Pharmaceuticals Ltd.

Unit Price : ৳ 50.00
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Brox

Navana Pharmaceuticals Ltd.

Unit Price : ৳ 30.00
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Broxidil

Ziska Pharmaceuticals Ltd.

Unit Price : ৳ 40.00
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Broxolit

Pacific Pharmaceuticals Ltd.

Unit Price : ৳ 25.00
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Cofexin

Globex Pharmaceuticals Ltd.

Unit Price : ৳ 35.00
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Dilyt

Navana Pharmaceuticals Ltd.

Unit Price : ৳ 40.13
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Emulyt

Amulet Pharmaceuticals Ltd.

Unit Price : ৳ 45.14
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Femex

Globe Pharmaceuticals Ltd.

Unit Price : ৳ 44:00
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Flintex

Oyster Pharmaceuticals Ltd.

Unit Price : ৳ 28.00
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Hybrox

Kemiko Pharmaceuticals Ltd.

Unit Price : ৳ 40.12
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Hybrox

Kemiko Pharmaceuticals Ltd.

Unit Price : ৳ 30.09
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Hybrox

Kemiko Pharmaceuticals Ltd.

Unit Price : ৳ 5.00
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Kashba

Alkad Laboratories

Unit Price : ৳ 45.00
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Kashba

Alkad Laboratories

Unit Price : ৳ 20.00
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Kickof

Guardian Healthcare Ltd.

Unit Price : ৳ 40.00
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Kofmelt

SMC Enterprise Ltd

Unit Price : ৳ 45.00
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Kufflin

Desh Pharmaceuticals Ltd.

Unit Price : ৳ 40.00
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Leucofil

Leon Pharmaceuticals Ltd.

Unit Price : ৳ 40.00
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Lytex

Ibn Sina Pharmaceuticals Ltd.

Unit Price : ৳ 50.00
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Lytex SR

Ibn Sina Pharmaceuticals Ltd.

Unit Price : ৳ 5.50
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M Boss

Central Pharmaceuticals Ltd.

Unit Price : ৳ 40.00
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Mbroxol

Benham Pharmaceuticals Ltd.

Unit Price : ৳ 50.00
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Mubrox

Hallmark Pharmaceuticals Ltd.

Unit Price : ৳ 30.20
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Mubrox

Hallmark Pharmaceuticals Ltd.

Unit Price : ৳ 20.00
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Mucobrox

Somatec Pharmaceuticals Ltd.

Unit Price : ৳ 43.00
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Mucobrox

Somatec Pharmaceuticals Ltd.

Unit Price : ৳ 30.00
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Mucoclean

Doctor TIMS Pharmaceuticals Ltd.

Unit Price : ৳ 40.00
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Mucosol

Beximco Pharmaceuticals Ltd.

Unit Price : ৳ 40.00
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Mucosol

Beximco Pharmaceuticals Ltd.

Unit Price : ৳ 30.00
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Mucovan

Ad-din Pharmaceuticals Ltd.

Unit Price : ৳ 47.00
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Muex

Avarox Pharmaceuticals Ltd.

Unit Price : ৳ 30.00
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Myrox

ACI Limited

Unit Price : ৳ 50.00
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Myrox

ACI Limited

Unit Price : ৳ 35.00
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Myrox SR

ACI Limited

Unit Price : ৳ 5.04
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Neobrox

Concord Pharmaceuticals Ltd.

Unit Price : ৳ 45.00
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Nexol

Aristopharma Ltd.

Unit Price : ৳ 40.00
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Nexol

Aristopharma Ltd.

Unit Price : ৳ 30.00
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Onecof

One Pharma Ltd.

Unit Price : ৳ 50.00
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Recof

Renata Limited

Unit Price : ৳ 40.00
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Recof

Renata Limited

Unit Price : ৳ 30.00
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Remap

Monicopharma Ltd.

Unit Price : ৳ 40.00
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Resol

Sharif Pharmaceuticals Ltd.

Unit Price : ৳ 40.12
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Rixol

Medicon Pharmaceuticals Ltd.

Unit Price : ৳ 50.00
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Roxal

Edruc Limited

Unit Price : ৳ 40.00
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Safoxol

Beacon Pharmaceuticals PLC

Unit Price : ৳ 50.00
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Safoxol

Beacon Pharmaceuticals PLC

Unit Price : ৳ 5.50
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Seebrox

Seema Pharmaceuticals Ltd.

Unit Price : ৳ 40.00
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Tembrox

Team Pharmaceuticals Ltd.

Unit Price : ৳ 47.00
🌿
Viscosol

UniMed UniHealth Pharmaceuticals Ltd.

Unit Price : ৳ 32.00
🌿
Viscosol

UniMed UniHealth Pharmaceuticals Ltd.

Unit Price : ৳ 50.00
🌿
WinkOF

Chemist Laboratories Ltd.

Unit Price : ৳ 50.00
🌿
X-Cold

ACME Laboratories Ltd.

Unit Price : ৳ 48.00
🌿
X-Cold

ACME Laboratories Ltd.

Unit Price : ৳ 35.00
🌿
Xerokof

Pharmasia Limited

Unit Price : ৳ 40.00