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Famotidine

Indications

Famotidine is indicated in-

  • Gastric ulcer
  • Duodenal ulcer
  • Anastomotic ulcer
  • Acute stress ulcer
  • Reflux esophagitis and
  • Zollinger-Ellison syndrome.

Famotidine is also indicated for the treatment of acute gastritis, chronic gastritis in the acute exacerbation stage.

* রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Pharmacology

Famotidine is a histamine H2-receptor antagonist. Famotidine completely inhibits the action of histamine on H2- receptors of parietal cell. It inhibits basal, overnight and pentagastrin stimulated gastric acid secretion. The H2- receptor antagonist activity of Famotidine is slowly reversible, since the drug dissociates slowly from H2-receptor.

Dosage & Administration

Tablet:

  • For gastric ulcer, duodenal ulcer, anastomotic ulcer, upper gastro-intestinal hemorrhage, reflux esophagitis and Zollinger-Ellison syndrome: Usual dose for adults: Famotidine 20 mg twice daily (after breakfast and after supper or before bed time) or Famotidine 40 mg can be administered orally once daily at bed time.
  • For the treatment of acute gastritis, chronic gastritis in acute exacerbation stage: Usual dosage for adults is Famotidine 20 mg orally twice a day (after breakfast and after supper or before bed time). Also Famotidine 40 mg can be orally administered once a day (before bed time), dosage should be adjusted according to age and symptoms. Most ulcer patients heal within 4-8 weeks. For maintenance therapy the recommended oral dose is 20 mg once daily. Or, as directed by the registered physician.

Powder for Suspension:
Gastroesophageal Reflux Disease(GERD):

  • <1 year of age: 0.5 mg/kg/dose of famotidine oral suspension up to 8 weeks once daily in patients
  • Age 3 to 11 months: 0.5 mg/kg/dose twice daily up to 8 weeks
  • Age 1 to 2 months: 0.5 mg/kg/dose once daily up to 8 weeks
  • Neonates: 0.5 mg/kg/dose maximum once daily up to 8 weeks

Patients 1-16 years of age:

  • Gastroesophageal Reflux Disease(GERD): 1 mg/kg/day p.o. divided b.i.d. up to 40 mg b.i.d.
  • Duodonal ulcer: 0.5 mg/kg/day p.o. at bedtime or divided b.i.d. up to 40 mg/day.
  • Peptic ulcer: 0.5 mg/kg/day p.o. at bedtime or divided b.i.d. up to 40 mg/day.
  • Maintenance therapy: 40 mg at daily night.
  • Reflux esophagitis: 2 mg/kg/day
  • Zollinger-Ellison Syndrome: 40 mg 3 times daily.

Interaction

No clinically important drug interactions have been identified. Famotidine does not interact with the cytochrome P450-linked drug-metabolizing enzyme system.

Contraindications

Known hypersensitivity to any component of the drug.

Side Effects

Eruption, constipation, diarrhoea, dry mouth, nausea, vomiting, tachycardia, high blood pressure, headache, drowsiness or insomnia may rarely occur.

Pregnancy & Lactation

Pregnancy category B. There are no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if clearly needed. Caution should be exercised when Famotid is administered to a nursing woman.

Precautions & Warnings

The drug should be used in the minimum required amount depending upon the conditions of the diseases. The drug should be administered carefully with elderly patients, patients with renal failure and hepatic disorders.

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Available Brand Names

🌿
Axidin

UniMed UniHealth Pharmaceuticals Ltd.

Unit Price : ৳ 2.00
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Axidin

UniMed UniHealth Pharmaceuticals Ltd.

Unit Price : ৳ 3.50
🌿
Famas

Ibn Sina Pharmaceuticals Ltd.

Unit Price : ৳ 50.00
🌿
Famas

Ibn Sina Pharmaceuticals Ltd.

Unit Price : ৳ 4.00
🌿
Famas

Ibn Sina Pharmaceuticals Ltd.

Unit Price : ৳ 2.00
🌿
Famisus

Ad-din Pharmaceuticals Ltd.

Unit Price : ৳ 48.0
🌿
Famodin

ACME Laboratories Ltd.

Unit Price : ৳ 4.00
🌿
Famodin

ACME Laboratories Ltd.

Unit Price : ৳ 3.50
🌿
Famogen

General Pharmaceuticals Ltd.

Unit Price : ৳ 55.00
🌿
Famoloc

Biopharma Limited

Unit Price : ৳ 50.00
🌿
Famoloc

Biopharma Limited

Unit Price : ৳ 4.00
🌿
Famoloc

Biopharma Limited

Unit Price : ৳ 2.00
🌿
Famomax

Beximco Pharmaceuticals Ltd.

Unit Price : ৳ 3.00
🌿
Famomax

Beximco Pharmaceuticals Ltd.

Unit Price : ৳ 3.00
🌿
Famomax

Beximco Pharmaceuticals Ltd.

Unit Price : ৳ 5.00
🌿
Famomax

Beximco Pharmaceuticals Ltd.

Unit Price : ৳ 50.00
🌿
Famomax

Beximco Pharmaceuticals Ltd.

Unit Price : ৳ 90.00
🌿
Famodin

ACME Laboratories Ltd.

Unit Price : ৳ 50.00
🌿
Famonix

Concord Pharmaceuticals Ltd.

Unit Price : ৳ 50.00
🌿
Famopep

Biogen Pharmaceuticals Ltd.

Unit Price : ৳ 2.00
🌿
Famosic

Physic pharmaceuticals ltd.

Unit Price : ৳ 47.00
🌿
Famotack

Square Pharmaceuticals PLC

Unit Price : ৳ 3.00
🌿
Famotack

Square Pharmaceuticals PLC

Unit Price : ৳ 5.00
🌿
Famotack

Square Pharmaceuticals PLC

Unit Price : ৳ 55.00
🌿
Famotid

Drug International Ltd.

Unit Price : ৳ 55.00
🌿
Famotid

Drug International Ltd.

Unit Price : ৳ 3.00
🌿
Famotid

Drug International Ltd.

Unit Price : ৳ 5.00
🌿
Famotin

Doctor’s Chemical Works Ltd.

Unit Price : ৳ 3.80
🌿
Famotin

Doctor’s Chemical Works Ltd.

Unit Price : ৳ 1.42
🌿
Nacid

Sonear Laboratories Ltd.

Unit Price : ৳ 2.05
🌿
NCR FAST

Pharmik Laboratories Ltd.

Unit Price : ৳ 3.80
🌿
NCR FAST

Pharmik Laboratories Ltd.

Unit Price : ৳ 2.00
🌿
Neostidine-R

Pristine Pharmaceuticals Ltd

Unit Price : ৳ 1.90
🌿
Peptid

Opsonin Herbal & Nutraceuticals Ltd.

Unit Price : ৳ 50.00
🌿
Peptid

Opsonin Pharma Ltd.

Unit Price : ৳ 3.81
🌿
Peptid

Opsonin Pharma Ltd.

Unit Price : ৳ 20.00
🌿
Peptid

Opsonin Pharma Ltd.

Unit Price : ৳ 1.92
🌿
Precid

Pharmasia Limited

Unit Price : ৳ 2.00
🌿
Precid

Pharmasia Limited

Unit Price : ৳ 48.00
🌿
Reducid

Incepta Pharmaceuticals Ltd.

Unit Price : ৳ 5.00
🌿
Reducid

Incepta Pharmaceuticals Ltd.

Unit Price : ৳ 5.00
🌿
Reducid

Incepta Pharmaceuticals Ltd.

Unit Price : ৳ 2.50
🌿
Reducid

Incepta Pharmaceuticals Ltd.

Unit Price : ৳ 50.00
🌿
Servipep

SANDOZ (A Novartis Division)

Unit Price : ৳ 4.00
🌿
Servipep

SANDOZ (A Novartis Division)

Unit Price : ৳ 6.10
🌿
Temtac

Team Pharmaceuticals Ltd.

Unit Price : ৳ 50.00
🌿
Temtac

Team Pharmaceuticals Ltd.

Unit Price : ৳ 2.00
🌿
Zactrol

Peoples Pharma Ltd.

Unit Price : ৳ 3.00