5HTP is indicated in-
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Each vegetable capsule contains-
5-Hydroxytryptophan (5HTP) is decarboxylated "in vivo" to yield serotonin, a neuro-hormonal transmitter released by neurons in the brain, spinal cord and symphatetic ganglia. Its seed contains active drug 5-hydroxytryptophan (5HTP). 5HTP is an aromatic amino acid naturally produced by the body from the essential amino acid L-tryptophan. Produced commercially by extraction from the seeds of the African plant Griffonia simplicifolia.
Valerian extract is effective in treating mild-to-moderate sleeping disorders without adverse effects on REM sleep and without significant hangover effects. Valerian has a sedative-hypnotics, anxiolytic, antidepressant, anticonvulsant and antispasmodic effects.
5HTP acts primarily by within the centralesing levels of serotonin nervous system. Other neurotransmitters and CNS chemicals, such as melatonin, dopamine, norepinephrine, and beta endorphin have also been shown to increase following oral administration of 5HTP.
Valepotriate binds to dopamine receptors. Valerenic acid also appears to inhibit the enzyme system responsible for the central catabolism of GABA, increasing GABA concentration and decreasing CNS activities.
Valerian extracts containing amino acids and valerenic acid bind with the GABA-A receptor. In the brain cortex.
Extract of Valerian inhibits the uptake and stimulates the release of GABA, leading to increase concentration of GABA in synaptic clefts. Valerenic acid may increasing inhibit enzymes that break down GABA, thus GABA levels and producing CNS-depressing effect.
1 or 2 vegetable capsules daily, or as per the instruction of a registered physician.
Carbidopa: Concurrent use may result in an increased risk of developing scleroderma- like illness in susceptible individuals.
Monoamine Oxidase Inhibitors (MAOIs) & Selective Serotonin Reuptake Inhibitors (SSRIs): Concurrent use may result in an increased risk of serotonin syndrome (Hypertension, hyperthermia, myoclonus, mental status changes). Combining 5HTP with SSRIS may increase the risk of serotonergic side effects. Valerian may potentiate the sedative effects of barbiturates, alcohol and benzodiazepines.
The World Health Organization (WHO) contraindicates the use of Valerian for children under 12 years without medical supervision.
Drowsiness
Nausea
Vomiting Stomach pain
Heartburn
Diarrhea
Loss of interest in sex
The use of 5HTP in pregnancy or lactation has not been determined in controlled trials; therefore, it should not be used during pregnancy.
Herbal and Nutraceuticals
Store in a cool & dry place, keep away from light & moisture. Keep out of reach of children.