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Vitamin B1, B6 & B12

Indications

Vitamin B1, B6 & B12 is indicated where a deficiency of the relevant vitamins exists. It is indicated for the treatment of following diseases: Polyneuropathy of any origin such alcoholic or toxiconeuropathies as-diabetic, Neuritis, Neuralgia, Cervical Syndrome, Shoulder-arm syndrome, Lumbago, Sciatica, Myalgia, Intercostal neuralgia, Herpes Zoster, Trigeminal Neuralgia, Supportive treatment in facial paresis.

* রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each film-coated tablet contains: Vitamin B1 (Thiamine Mononitrate) 100 mg, Vitamin B6 (Pyridoxine Hydrochloride) 200 mg, Vitamin B12 (Cyanocobalamin) 200 microgram.
Each 3 ml ampoule contains: Thiamine Hydrochloride (Vitamin B1) 100 mg, Pyridoxine Hydrochloride (Vitamin B6) 100 mg, Cyanocobalamin (Vitamin B12) 1000 mcg.

Pharmacology

Vitamin B1 converts carbohydrates, fatty acids and amino acids into energy, promotes healthy nerves, improves mood, strengthens the heart. Vitamin B6 forms RBCs, helps cells to make proteins, manufactures neurotransmitters e.g. serotonin and releases stored forms of energy, helps to prevent CVS diseases and stroke, helps to lift depression and eases insomnia. Vitamin B12 is essential for cell replication and important for RBC production, prevents anemia, helps to prevent depression, reduces nerve pain, numbness, tingling and lowers the risk of heart diseases.

The vitamin ingredients are absorbed well in per oral reception. It is widely distributed to most tissues and appears in breast milk. Within the cell, thiamine is mostly present as diphosphate. Thiamine is not stored to any appreciable extent in the body and amounts in excess of the body’s requirements are excreted in the urine as unchanged thiamine or as metabolites. Pyridoxine, pyridoxal and pyridoxamine are readily absorbed from the GIT following oral administration and are converted to the active forms of pyridoxal phosphate an pyridoxamine phosphate. They are stored mainly in liver where there is oxidation to 4-pyridoxic acid and other inactive metabolites, which are excreted in urine. As the dose increases, proportionally greater amounts are excreted unchanged in the urine.

Dosage & Administration

Tablet: 1-3 Tablets per day or as advised by the physician.

Injection:

  • In severe (acute) cases: 1 injection daily until the acute symptoms subside or taken as advised by the physician.
  • In mild cases: 1 injection 2-3 times per week. Ampoules are preferably injected intramuscularly.

Use in children: There is no information on the use of this drug in children.

Interaction

No drug interaction has been reported yet.

Contraindications

Vitamin B1, Vitamin B6 and Vitamin B12 is contraindicated in patients on levodopa therapy, and in patients with hypersensitivity to any of the ingredients of the preparation.

Side Effects

Generally well tolerated but allergic reactions may be observed in few cases.

Pregnancy & Lactation

Oral tablet form is recommended but due to the presence of benzyl alcohol, injection is not recommended during pregnancy & lactation.

Precautions & Warnings

Cyanocobalamin should not be given in patients with subacute degeneration of the spinal cord. Cyanocobalamin is not suitable form of vitamin B12 for the treatment of optic neuropathies associated with raised plasma concentrations of cyanocobalamin.

Therapeutic Class

Specific combined vitamin preparations, Vaccines, Anti-sera & Immunoglobulin

Storage Conditions

Keep out of reach of children. Store in a cool (below 25°C temperature) and dry place, protected from light.

Common Questions

What is this combination?

  • Vitamin B1 converts carbohydrates, fatty acids and amino acids into energy,
  • Vitamin B6 forms RBCs,
  • Vitamin B12 is essential for cell replication.

What is this combination used for?

This combination is indicated where a deficiency of the relevant vitamins exists.

Overdose Effects

No overdosage symptoms are to be expected in the recommended dosage. If there is known overdose then treatment is symptomatic & supportive.

Available Brand Names

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Becobion

Beacon Pharmaceuticals PLC

Unit Price : ৳ 25.00

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Bfill

Maks Drug Limited

Unit Price : ৳ 9.00

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Becobion

Beacon Pharmaceuticals PLC

Unit Price : ৳ 13.00

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B3

Al-Madina Pharmaceuticals Ltd.

Unit Price : ৳ 7.00

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B126

Popular Pharmaceuticals Ltd.

Unit Price : ৳ 12.00

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Axovit

Doctor TIMS Pharmaceuticals Ltd.

Unit Price : ৳ 7.00

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Astra-N

Astra Biopharmaceuticals Ltd.

Unit Price : ৳ 7.00

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Astra-N

Astra Biopharmaceuticals Ltd.

Unit Price : ৳ 7.00

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Asibion

Asiatic Laboratories Ltd.

Unit Price : ৳ 5.00

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Alvita

Albion Laboratories Limited

Unit Price : ৳ 7.00

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3 Bion

Jenphar Bangladesh Ltd.

Unit Price : ৳ 12.00

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D-Vital

Doctor’s Chemical Works Ltd.

Unit Price : ৳ 6.00

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D-Vital

Doctor’s Chemical Works Ltd.

Unit Price : ৳ 6.00

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Cyano-B

Avarox Pharmaceuticals Ltd.

Unit Price : ৳ 4.00

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Costa-B

Nuvista Pharma Ltd.

Unit Price : ৳ 8.00

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Combomin

Ad-din Pharmaceuticals Ltd.

Unit Price : ৳ 12.00

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Centobion

Centeon Pharma Ltd.

Unit Price : ৳ 8.00

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Bost

General Pharmaceuticals Ltd.

Unit Price : ৳ 12.00

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Bionic

Pharmasia Limited

Unit Price : ৳ 12.00

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Big B

Amico Laboratories Ltd.

Unit Price : ৳ 6.00

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Bionic

Pharmasia Limited

Unit Price : ৳ 25.00

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Bost

General Pharmaceuticals Ltd.

Unit Price : ৳ 30.00

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Kvit-N

Kemiko Pharmaceuticals Ltd.

Unit Price : ৳ 25.07

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Ethibion

Ethical Drugs Limited

Unit Price : ৳ 25.00

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Edruplex

Edruc Limited

Unit Price : ৳ 25.00

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Kvit-N

Kemiko Pharmaceuticals Ltd.

Unit Price : ৳ 8.00

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Kvit-N

Kemiko Pharmaceuticals Ltd.

Unit Price : ৳ 8.00

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Jeuneau-B

Arges Life Science Limited

Unit Price : ৳ 8.00

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Ethibion

Ethical Drugs Limited

Unit Price : ৳ 7.00

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Getbion

Get Well Limited

Unit Price : ৳ 8.00

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Edruplex

Edruc Limited

Unit Price : ৳ 8.00

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Ebion

Biogen Pharmaceuticals Ltd.

Unit Price : ৳ 7.00

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Debion

Delta Pharma Ltd.

Unit Price : ৳ 7.00

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Nerbo

Sharif Pharmaceuticals Ltd.

Unit Price : ৳ 8.00

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Neovitan

Techno Drugs Ltd.

Unit Price : ৳ 8.00

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Neobion

Aristopharma Ltd.

Unit Price : ৳ 12.00

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Nenvit

Euro Pharma Ltd.

Unit Price : ৳ 8.00

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Nenvit

Euro Pharma Ltd.

Unit Price : ৳ 8.00

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N-Vit

MST Pharma

Unit Price : ৳ 5.00

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N-bion

Navana Pharmaceuticals Ltd.

Unit Price : ৳ 10.00

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Myobion

Kumudini Pharma Ltd.

Unit Price : ৳ 10.00

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Myelin

Opsonin Pharma Ltd.

Unit Price : ৳ 9.00

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Miovit

Somatec Pharmaceuticals Ltd.

Unit Price : ৳ 8.00

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Medibion

Medicon Pharmaceuticals Ltd.

Unit Price : ৳ 8.00

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Myelin

Opsonin Pharma Ltd.

Unit Price : ৳ 25.09

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N-bion

Navana Pharmaceuticals Ltd.

Unit Price : ৳ 25.00

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Neovitan

Techno Drugs Ltd.

Unit Price : ৳ 25.00

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Neobion

Aristopharma Ltd.

Unit Price : ৳ 30.00

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Nerv B

Gaco Pharmaceuticals Ltd.

Unit Price : ৳ 8.00

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Nerva

Pharmadesh Laboratories Ltd.

Unit Price : ৳ 4.50

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Nerviplex

Jayson Pharmaceutical Ltd.

Unit Price : ৳ 7.00

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Nervopex

Apex Pharmaceuticals Ltd.

Unit Price : ৳ 9.00

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Nervotil

DBL Pharmaceuticals Ltd.

Unit Price : ৳ 10.00

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Nerviplex

Jayson Pharmaceutical Ltd.

Unit Price : ৳ 25.17

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Neubin

Ziska Pharmaceuticals Ltd.

Unit Price : ৳ 25.00

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Neto B

National Drug Co. Ltd.

Unit Price : ৳ 9.00

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Neu-3

Cosmic Pharma Ltd.

Unit Price : ৳ 7.00

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Neubin

Ziska Pharmaceuticals Ltd.

Unit Price : ৳ 9.00

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Neucent

C2C Pharma Ltd.

Unit Price : ৳ 8.00

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Neucos-B

Radiant Pharmaceuticals Ltd.

Unit Price : ৳ 12.00

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Neuralgin

Ibn Sina Pharmaceuticals Ltd.

Unit Price : ৳ 6.00

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Neurep

Biopharma Limited

Unit Price : ৳ 8.00

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Neurex-B

Silva Pharmaceuticals Ltd.

Unit Price : ৳ 8.00

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Neuro Vitamin

Premier Pharmaceuticals Ltd.

Unit Price : ৳ 7.00

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Neuro Vitamin

Premier Pharmaceuticals Ltd.

Unit Price : ৳ 7.00

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Neuralgin

Ibn Sina Pharmaceuticals Ltd.

Unit Price : ৳ 30.00

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Neuro-B

Square Pharmaceuticals PLC

Unit Price : ৳ 30.00

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Neurobest

Renata Limited

Unit Price : ৳ 30.00

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Neuro-B

Square Pharmaceuticals PLC

Unit Price : ৳ 10.00

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Neuro-B

Square Pharmaceuticals PLC

Unit Price : ৳ 10.00

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Neuroaid

Novo Healthcare and Pharma Ltd.

Unit Price : ৳ 5.02

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Neurobest

Renata Limited

Unit Price : ৳ 10.00

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Neurocare

Beximco Pharmaceuticals Ltd.

Unit Price : ৳ 10.00

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Neurocon

Novelta Bestway Pharma Ltd.

Unit Price : ৳ 5.00

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Neurocone

Pharmik Laboratories Ltd.

Unit Price : ৳ 7.00

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Neurodol

Rangs Pharmaceuticals Ltd.

Unit Price : ৳ 8.00

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Neurogin

Silco Pharmaceutical Ltd.

Unit Price : ৳ 6.50

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Neurogin

Silco Pharmaceutical Ltd.

Unit Price : ৳ 6.50

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Neuromate

Labaid Pharma Ltd.

Unit Price : ৳ 10.00

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Neuroprax

Concord Pharmaceuticals Ltd.

Unit Price : ৳ 9.00

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Neuroprax

Concord Pharmaceuticals Ltd.

Unit Price : ৳ 9.00

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Neuroson

Hudson Pharmaceuticals Ltd.

Unit Price : ৳ 8.00

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Neurotonic

Globex Pharmaceuticals Ltd.

Unit Price : ৳ 5.00

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Neuroxen

Everest Pharmaceuticals Ltd.

Unit Price : ৳ 12.00

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Neurotonic

Globex Pharmaceuticals Ltd.

Unit Price : ৳ 25.00

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Neutos

Union Pharmaceuticals Ltd

Unit Price : ৳ 8.00

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Nugesic

Orion Pharma Ltd.

Unit Price : ৳ 25.17

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Nugesic

Orion Pharma Ltd.

Unit Price : ৳ 9.00

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Neuvit Plus

United Pharmaceuticals Ltd.

Unit Price : ৳ 7.00

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NeuVital

UniMed UniHealth Pharmaceuticals Ltd.

Unit Price : ৳ 9.00

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Nevrona

One Pharma Ltd.

Unit Price : ৳ 9.00

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Nevrona

One Pharma Ltd.

Unit Price : ৳ 9.00

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Nins

Benham Pharmaceuticals Ltd.

Unit Price : ৳ 11.00

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Nopath

Amulet Pharmaceuticals Ltd.

Unit Price : ৳ 5.02

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Nurobix Plus

Chemist Laboratories Ltd.

Unit Price : ৳ 8.50

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Nuroguard

Guardian Healthcare Ltd.

Unit Price : ৳ 5.00

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Nuronaaf

Naafco Pharma Ltd.

Unit Price : ৳ 12.00

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Nuropa

Nipa Pharmaceuticals Ltd.

Unit Price : ৳ 7.00

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Nurowel

SMC Enterprise Ltd

Unit Price : ৳ 7.50

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Orgabion

Novatek Pharmaceuticals Ltd.

Unit Price : ৳ 8.00

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OST

Central Pharmaceuticals Ltd.

Unit Price : ৳ 4.00

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Pacibion

Pacific Pharmaceuticals Ltd.

Unit Price : ৳ 9.00

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Povital

ACI Limited

Unit Price : ৳ 12.00

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Pristibion

Pristine Pharmaceuticals Ltd

Unit Price : ৳ 7.00

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Pacibion

Pacific Pharmaceuticals Ltd.

Unit Price : ৳ 25.00

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Povital

ACI Limited

Unit Price : ৳ 25.17

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Renovit

Healthcare Pharmaceuticals Ltd.

Unit Price : ৳ 28.00

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Rejubion

Beacon Pharmaceuticals PLC

Unit Price : ৳ 25.17

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Rebion

Rephco Pharmaceuticals Ltd.

Unit Price : ৳ 25.00

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Rebion

Rephco Pharmaceuticals Ltd.

Unit Price : ৳ 8.33

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Rejubion

Beacon Pharmaceuticals PLC

Unit Price : ৳ 8.00

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Renep

Alco Pharma Ltd.

Unit Price : ৳ 8.00

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Renovit

Healthcare Pharmaceuticals Ltd.

Unit Price : ৳ 9.00

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SB-Neurec

Sunman-Birdem Pharma Ltd.

Unit Price : ৳ 8.00

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Serobion

Leon Pharmaceuticals Ltd.

Unit Price : ৳ 5.00

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Serobion

Leon Pharmaceuticals Ltd.

Unit Price : ৳ 5.00

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Solbion

Eskayef Pharmaceuticals Ltd.

Unit Price : ৳ 10.00

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Solbion

Eskayef Pharmaceuticals Ltd.

Unit Price : ৳ 10.00

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Spine-B

Novus Pharmaceuticals Ltd.

Unit Price : ৳ 4.00

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Supra-B

Drug International Ltd.

Unit Price : ৳ 9.00

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Supra-B

Drug International Ltd.

Unit Price : ৳ 25.00

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Solbion

Eskayef Pharmaceuticals Ltd.

Unit Price : ৳ 25.00

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Temvit-N

Team Pharmaceuticals Ltd.

Unit Price : ৳ 9.00

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Temvit-N

Team Pharmaceuticals Ltd.

Unit Price : ৳ 9.00

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TPC

ACME Laboratories Ltd.

Unit Price : ৳ 11.00

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Tri-B

The White Horse Pharmaceuticals Ltd.

Unit Price : ৳ 9.00

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Tribion

Globe Pharmaceuticals Ltd.

Unit Price : ৳ 9.00

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Trilin B

OSL Pharma Limited

Unit Price : ৳ 11.00

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Tribion

Globe Pharmaceuticals Ltd.

Unit Price : ৳ 25.00

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TPC

ACME Laboratories Ltd.

Unit Price : ৳ 25.17

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Unibion

Desh Pharmaceuticals Ltd.

Unit Price : ৳ 8.00

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V-Nerve

Monicopharma Ltd.

Unit Price : ৳ 4.00

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V3N

NIPRO JMI Pharma Ltd.

Unit Price : ৳ 10.00

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VB-3

Cosmo Pharma Laboratories Ltd.

Unit Price : ৳ 8.00

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Verita-B

Veritas Pharmaceuticals Ltd.

Unit Price : ৳ 7.00

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Vigor

Hallmark Pharmaceuticals Ltd.

Unit Price : ৳ 4.00

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Virobion

Virgo Pharmaceuticals Ltd.

Unit Price : ৳ 5.00

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Vitabion

Incepta Pharmaceuticals Ltd.

Unit Price : ৳ 12.00

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Vitanerv

Goodman Pharmaceuticals Ltd.

Unit Price : ৳ 8.00

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VN

Reliance Pharmaceuticals Ltd.

Unit Price : ৳ 4.00

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Zenbion

Zenith Pharmaceuticals Ltd.

Unit Price : ৳ 7.00

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V-Nerve

Monicopharma Ltd.

Unit Price : ৳ 25.00

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Vitabion

Incepta Pharmaceuticals Ltd.

Unit Price : ৳ 28.00